Popular conclusion:
"... Aging is associated both with calcium deficiency, due to low
dietary intake and decreased intestinal absorption, and with vitamin D
deficiency, secondary to depletion of body stores resulting from inadequate
exposure to sunlight. Hepatic hydroxylation of vitamin D remains normal
in elderly individuals. Recent data suggest that renal hydroxylation of
vitamin D, previously believed to decrease with advancing age, also remains
virtually normal even when creatinine clearance declines, as is very often
the case in elderly patients. The combined deficiency in calcium and vitamin
D stimulates the secretion of parathyroid hormone which tends to normalize
serum calcium levels and causes the bone disorders of senile osteoporosis."
(
Rev Rhum Ed Fr 1993 Jun;60(6):445-9: Benhamou CL; Tourliere
D; Asselin F
Influence of aging on vitamin D metabolism.)
.
" ...The consequences of calcium deficiency might thus include
not only osteoporosis, but also arteriosclerosis and hypertension due to
the increase of calcium in the vascular wall, amyotrophic lateral sclerosis
and senile dementia due to calcium deposition in the central nervous system,
and a decrease in cellular function, because of blunting of the difference
in extracellular-intracellular calcium, leading to diabetes mellitus, immune
deficiency and others ..." (
J Nutr Sci Vitaminol (Tokyo) 1985 Dec;31 Suppl:S15-9: Fujita
T
Aging and calcium as an environmental factor.)
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